Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Anion Binding as a Probe of the Pore

Identification of the Cystic Fibrosis Gene: Cloning and Characterization of Complementary DNA

John R. Riordan, Johanna M. Rommens, Bat-Sheva Kerem et al. · Science · 1989 · 7.4K citations

Genetics, Molecular Biology, Pathology +17

Therapy of CF-Patients with Amitriptyline and Placebo - a Randomised, Double-Blind, Placebo-Controlled Phase IIb Multicenter, Cohort-Study

Lutz Nährlich, Jochen G. Mainz, Constantin Adams et al. · Cellular Physiology and Biochemistry · 2013 · 2.5K citations · Full text

Charge density-dependent strength of hydration and biological structure

Kim D. Collins · Biophysical Journal · 1997 · 1.3K citations · Full text

Charge Density-dependent Strength, Biophysics, Physicochemical Analysis

Demonstration That CFTR Is a Chloride Channel by Alteration of Its Anion Selectivity

Matthew P. Anderson, Richard J. Gregory, Simon Thompson et al. · Science · 1991 · 1.1K citations

Purification and functional reconstitution of the cystic fibrosis transmembrane conductance regulator (CFTR)

Christine E. Bear, Canhui Li, Norbert Kartner et al. · Cell · 1992 · 943 citations

Protein Secretion, Fibrosis, Signal Transduction +11