Synthesis of Biocompatible Dextran‐Coated Nanoceria with pH‐Dependent Antioxidant Properties

Abstract

Biocompatible dextran-coated nanoceria (cerium oxide nanoparticles) are found to exhibit excellent, pH-dependent antioxidant properties (see image). They provide cytoprotection from free radicals to normal cells but not to cancer cells, and thus have potential applications in antioxidant and anti-inflammatory coatings for prosthetic devices and tissue engineering and in improved cancer therapeutics. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2296/2008/smll200700824_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.