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A novel series of 2-pyridyl-containing compounds as lysophosphatidic acid receptor antagonists: development of a nonhydrolyzable LPA3 receptor-selective antagonist

Brian Heasley, Renata Jarosz, Karen M. Carter, S Jenny Van, Kevin R. Lynch, Timothy L. Macdonald

Bioorganic & Medicinal Chemistry Letters · 2004 · 29 citations · 16 references

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References

16

Stereoselective Synthesis of β‐Amino Alcohols from Optically Active α‐Amino Acids

Manfred T. Reetz, M. W. Drewes, Alfred Schmitz · Angewandte Chemie International Edition in English · 1987 · 253 citations

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Molecular Cloning and Characterization of a Lysophosphatidic Acid Receptor, Edg-7, Expressed in Prostate

Dong‐Soon Im, Christopher E. Heise, Michael A. Harding et al. · Molecular Pharmacology · 2000 · 199 citations

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Self-Consistent Spectrophotometric Basicity Scale in Acetonitrile Covering the Range between Pyridine and DBU

Ivari Kaljurand, Toomas Rodima, Ivo Leito et al. · The Journal of Organic Chemistry · 2000 · 187 citations

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Lysophosphatidic Acid-induced Mitogenesis Is Regulated by Lipid Phosphate Phosphatases and Is Edg-receptor Independent

Shelley B. Hooks, Webster L. Santos, Dong‐Soon Im et al. · Journal of Biological Chemistry · 2001 · 133 citations · Full text

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Steric Effects in Displacement Reactions. III. The Base Strengths of Pyridine, 2,6-Lutidine and the Monoalkylpyridines

Herbert C. Brown, Xavier R. Mihm · Journal of the American Chemical Society · 1955 · 128 citations

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