Concepedia

Implementation of a Fluorescence-Based Screening Assay Identifies Histamine H3 Receptor Antagonists Clobenpropit and Iodophenpropit as Subunit-Selective N-Methyl-d-Aspartate Receptor Antagonists

Kasper B. Hansen, Praseeda Mullasseril, Sara Dawit, Natalie L. Kurtkaya, Hongjie Yuan, Katie M. Vance, Anna G. Orr, Trine Kvist, Kevin K. Ogden, Phuong Le,

Journal of Pharmacology and Experimental Therapeutics · 2010 · 44 citations · 33 references

Open access

References

33

A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

Ji-Hu Zhang, Thomas D.Y. Chung, Kevin R. Oldenburg · SLAS DISCOVERY · 1999 · 7K citations · Full text

Pharmacy, Medicinal Chemistry, Drug Design +16

Potential energy functions for atomic-level simulations of water and organic and biomolecular systems

William L. Jorgensen, Julian Tirado‐Rives · Proceedings of the National Academy of Sciences · 2005 · 1.6K citations · Full text

Natural Sciences, Chemistry, Physics +16

Comparison of Shape-Matching and Docking as Virtual Screening Tools

Paul C. D. Hawkins, A. Geoffrey Skillman, Anthony Nicholls · Journal of Medicinal Chemistry · 2006 · 1K citations

Pharmacy, Medicinal Chemistry, Drug Design +10

Functional and Pharmacological Differences Between Recombinant<i>N</i>-Methyl-<scp>d</scp>-Aspartate Receptors

Stefano Vicini, Jianfeng Wang, Jin Hong Li et al. · Journal of Neurophysiology · 1998 · 675 citations

Life Sciences, Neuroscience, Pharmacology +17

An Innovative Design to Establish Proof of Concept of the Antidepressant Effects of the NR2B Subunit Selective N-Methyl-D-Aspartate Antagonist, CP-101,606, in Patients With Treatment-Refractory Major Depressive Disorder

Sheldon Preskorn, Bryan Baker, Sheela Kolluri et al. · Journal of Clinical Psychopharmacology · 2008 · 511 citations

Medicine, Pharmacology, Pharmacotherapy +17