Induction of leptin resistance through direct interaction of C-reactive protein with leptin

Positional cloning of the mouse obese gene and its human homologue

Yiying Zhang, Ricardo Proenca, Margherita Maffei et al. · Nature · 1994 · 13.4K citations

Life Sciences, Genetics, Molecular Genetics +12

Identification and expression cloning of a leptin receptor, OB-R

Louis A. Tartaglia, Marlene Dembski, Xun Weng et al. · Cell · 1995 · 3.5K citations · Full text

Life Sciences, Endocrinology, Molecular Biology +10

Abnormal splicing of the leptin receptor in diabetic mice

Gwo‐Hwa Lee, R Proenca, Jason Montez et al. · Nature · 1996 · 2.4K citations

Life Sciences, Endocrinology, Molecular Biology +13

Recombinant Leptin for Weight Loss in Obese and Lean Adults

Steven B. Heymsfield, Andrew S. Greenberg, Ken Fujioka et al. · JAMA · 1999 · 1.4K citations

Agriculture, Endocrinology, Nutrition +15

Leptin activation of Stat3 in the hypothalamus of wild–type and ob/ob mice but not db/db mice

Christian Vaisse, Jeffrey L. Halaas, Curt M. Horvath et al. · Nature Genetics · 1996 · 1.1K citations

Life Sciences, Endocrinology, Physiology +15