The endoplasmic reticulum stress markers GRP78 and CHOP predict disease-free survival and responsiveness to chemotherapy in breast cancer

Prognostic and predictive factors in breast cancer by immunohistochemical analysis.

D. Craig Allred, Jennet Harvey, Melora D. Berardo et al. · PubMed · 1998 · 2.2K citations

CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum

Stefan J. Marciniak, Chi Young Yun, Seiichi Oyadomari et al. · Genes & Development · 2004 · 2K citations · Full text

Er Oxidase, Lipid Peroxidation, Apoptosis +20

REporting recommendations for tumor MARKer prognostic studies (REMARK)

Lisa M. McShane, Douglas G. Altman, Willi Sauerbrei et al. · Breast Cancer Research and Treatment · 2006 · 801 citations

Prognostic Evaluation, Prognostic Biomarkers, Medicine +4

Adaptation to ER Stress Is Mediated by Differential Stabilities of Pro-Survival and Pro-Apoptotic mRNAs and Proteins

D. Thomas Rutkowski, Stacey Arnold, Corey N. Miller et al. · PLoS Biology · 2006 · 793 citations · Full text

Apoptosis, Cell Death, Pro-apoptotic Mrnas +16

Two Distinct Stress Signaling Pathways Converge Upon the CHOP Promoter During the Mammalian Unfolded Protein Response

Yanjun Ma, Joseph W. Brewer, J. Alan Diehl et al. · Journal of Molecular Biology · 2002 · 685 citations

Systems Biology, Protein Expression, Chop Promoter +8