Concepedia

Specific inhibition of gene expression using a stably integrated, inducible small‐interfering‐RNA vector

Marc van de Wetering, Irma M. Oving, Vanesa Muncan, Menno Tjon Pon Fong, Helen Brantjes, Dik van Leenen, Frank C. P. Holstege, Thijn R. Brummelkamp, Reuven Agami, Hans Clevers

EMBO Reports · 2003 · 508 citations · 23 references

DOIFull text

Open access

Concepts

References

23

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

Sayda M. Elbashir, Jens Harborth, Winfried Lendeckel et al. · Nature · 2001 · 9.4K citations

, , +7

Tight control of gene expression in mammalian cells by tetracycline-responsive promoters.

Manfred Gossen, Heidelberg Bujard · Proceedings of the National Academy of Sciences · 1992 · 5K citations

, , +17

A System for Stable Expression of Short Interfering RNAs in Mammalian Cells

Thijn R. Brummelkamp, René Bernards, Reuven Agami · Science · 2002 · 4.3K citations · Full text

, , +16

Activation of β-Catenin-Tcf Signaling in Colon Cancer by Mutations in β-Catenin or APC

Patrice J. Morin, Andrew B. Sparks, Vladimír Kořínek et al. · Science · 1997 · 3.9K citations

, , +17

Constitutive Transcriptional Activation by a β-Catenin-Tcf Complex in APC <sup>−/−</sup> Colon Carcinoma

Vladimír Kořínek, Nick Barker, Patrice J. Morin et al. · Science · 1997 · 3.3K citations

, , +17