Dik van Leenen

Mammalian Cry1 and Cry2 are essential for maintenance of circadian rhythms

Gijsbertus T. J. van der Horst, Manja Muijtjens, Kumiko Kobayashi et al. · Nature · 1999 · 1.4K citations

Signal Transduction, Medicine, Mammalian Physiology +9

Specific inhibition of gene expression using a stably integrated, inducible small‐interfering‐RNA vector

Marc van de Wetering, Irma M. Oving, Vanesa Muncan et al. · EMBO Reports · 2003 · 508 citations · Full text

Specific Inhibition, Natural Sciences, Rna Biology +10

Large-Scale Genetic Perturbations Reveal Regulatory Networks and an Abundance of Gene-Specific Repressors

Patrick Kemmeren, Katrin Sameith, Loes A. L. van de Pasch et al. · Cell · 2014 · 304 citations · Full text

Systems Biology, Functional Genomics, Engineering +12

The Specificity and Topology of Chromatin Interaction Pathways in Yeast

Tineke L. Lenstra, Joris J. Benschop, Tae Soo Kim et al. · Molecular Cell · 2011 · 247 citations · Full text

Chromatin, Cell Division, Chromatin Remodeling +11

Mediator Expression Profiling Epistasis Reveals a Signal Transduction Pathway with Antagonistic Submodules and Highly Specific Downstream Targets

Jeroen van de Peppel, Nienke Kettelarij, Harm van Bakel et al. · Molecular Cell · 2005 · 215 citations · Full text

Systems Biology, Functional Genomics, Signal Transduction +14