Concepedia

First report of polymorphisms in the prion-like protein gene (PRND): implications for human prion diseases

Katell Peoc’h, Caroline Guérin, Jean‐Philippe Brandel, Jean-Marie Launay, Jean Laplanche

Neuroscience Letters · 2000 · 76 citations · 17 references

Concepts

Veterinary MedicineGeneticsMolecular GeneticsGenomicsHuman GeneticsPrion DiseasesFamilial Prion DiseaseNeuropathology Of Prion DiseasePrion Protein MisfoldingGenetic Prion Protein MutationsPolymorphisms At Codon 129Prion Disease PathologyPrion PathogenesisPrion Protein Gene SequencingPrion Protein Misfolding PatternsStructural Polymorphism Of Prions

References

17

Identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites

Henrik Nielsen, Jacob Engelbrecht, Søren Brunak et al. · Protein Engineering Design and Selection · 1997 · 5.4K citations · Full text

Life Sciences, Bioinformatics, Molecular Biology +17

Novel Proteinaceous Infectious Particles Cause Scrapie

Stanley B. Prusiner · Science · 1982 · 5.1K citations

Veterinary Medicine, Infectious Diseases, Molecular Biology +10

A new method for predicting signal sequence cleavage sites

Gunnar von Heijne · Nucleic Acids Research · 1986 · 4.6K citations · Full text

Life Sciences, Bioinformatics, Biology +11

A knowledge base for predicting protein localization sites in eukaryotic cells

Kenta Nakai, Minoru Kanehisa · Genomics · 1992 · 1.5K citations · Full text

Life Sciences, Bioinformatics, Molecular Biology +13

Homozygous prion protein genotype predisposes to sporadic Creutzfeldt–Jakob disease

Mark S. Palmer, Aidan J. Dryden, John T. Hughes et al. · Nature · 1991 · 897 citations

Life Sciences, Genetics, Neurology +13