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THE EFFECT OF CIMETIDINE ON DEXTROMETHORPHAN O-DEMETHYLASE ACTIVITY OF HUMAN LIVER MICROSOMES AND RECOMBINANT CYP2D6

Maria Madeira, Marc Levine, Thomas K. H. Chang, Ahmad Mirfazaelian, Gail D. Bellward

Drug Metabolism and Disposition · 2004 · 46 citations · 31 references

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References

31

Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.

Deborah J. Newton, R W Wang, Anthony Y.H. Lu · Drug Metabolism and Disposition · 1995 · 606 citations

, , +17

Lipid peroxidation and the degradation of cytochrome P-450 heme

Wayne Levin, Anthony Y.H. Lu, Martin Jacobson et al. · Archives of Biochemistry and Biophysics · 1973 · 226 citations

, , +13

The CYP2D6 Humanized Mouse: Effect of the Human CYP2D6 Transgene and HNF4 on the Disposition of Debrisoquine in the Mouse

Javier Corchero, Camille Granvil, Taro E. Akiyama et al. · Molecular Pharmacology · 2001 · 139 citations

, , +16

Comparative contribution to dextromethorphan metabolism by cytochrome P450 isoforms in vitro: can dextromethorphan be used as a dual probe for both CTP2D6 and CYP3A activities?

Ai‐Ming Yu, Robert L. Haining · PubMed · 2001 · 136 citations

, , +16

Comparative in vitro and in vivo inhibition of cytochrome P450 CYP1A2, CYP2D6, and CYP3A by H -receptor antagonists

C Albet, José A. G. Agúndez, Juan Antonio Carrillo et al. · Clinical Pharmacology & Therapeutics · 1999 · 132 citations

, , +17