Concepedia

Loss of intestinal crypt progenitor cells owing to inactivation of both Notch1 and Notch2 is accompanied by derepression of CDK inhibitors p27Kip1 and p57Kip2

Orbicia Riccio, Mariëlle van Gijn, April Candice Bezdek, Luca Pellegrinet, Johan H. van Es, Ursula Zimber‐Strobl, Lothar J. Strobl, Tasuku Honjo, Hans Clevers, Freddy Radtke

EMBO Reports · 2008 · 405 citations · 19 references

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19

The β-Catenin/TCF-4 Complex Imposes a Crypt Progenitor Phenotype on Colorectal Cancer Cells

Marc van de Wetering, Elena Sancho, Cornelis L. Verweij et al. · Cell · 2002 · 2K citations · Full text

, , +16

Nod2-Dependent Regulation of Innate and Adaptive Immunity in the Intestinal Tract

Koichi S. Kobayashi, Mathias Chamaillard, Yasunori Ogura et al. · Science · 2005 · 1.8K citations

, , +17

Notch/γ-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells

Johan H. van Es, Mariëlle van Gijn, Orbicia Riccio et al. · Nature · 2005 · 1.5K citations · Full text

, , +15

Deficient T Cell Fate Specification in Mice with an Induced Inactivation of Notch1

Freddy Radtke, Anne E. Wilson, Gerlinde Stark et al. · Immunity · 1999 · 1.4K citations · Full text

, , +14

Control of endodermal endocrine development by Hes-1

Jan Jensen, Erna Engholm Pedersen, Philip Galante et al. · Nature Genetics · 2000 · 1.1K citations

, , +12