Simultaneous analysis of relative protein expression levels across multiple samples using iTRAQ isobaric tags with 2D nano LC–MS/MS

Multiplexed Protein Quantitation in Saccharomyces cerevisiae Using Amine-reactive Isobaric Tagging Reagents

Philip L. Ross, Yulin Huang, Jason Marchese et al. · Molecular & Cellular Proteomics · 2004 · 4.4K citations · Full text

Tandem Mass Tags:  A Novel Quantification Strategy for Comparative Analysis of Complex Protein Mixtures by MS/MS

Andrew Thompson, Jürgen Schäfer, Karsten Kuhn et al. · Analytical Chemistry · 2003 · 2.4K citations

Biological Mass Spectrometry, Molecular Biology, Tandem Mass Tags +21

Protein labeling by iTRAQ: A new tool for quantitative mass spectrometry in proteome research

Sebastian Wiese, Kai A. Reidegeld, Helmut E. Meyer et al. · PROTEOMICS · 2006 · 796 citations

Protein Analysis, Molecular Biology, Protein Purification +21

Time-resolved Mass Spectrometry of Tyrosine Phosphorylation Sites in the Epidermal Growth Factor Receptor Signaling Network Reveals Dynamic Modules

Yi Zhang, Alejandro Wolf‐Yadlin, Phillip Ross et al. · Molecular & Cellular Proteomics · 2005 · 547 citations · Full text

Immunology, Biological Mass Spectrometry, Tyrosine Phosphorylation Sites +18

Multiple reaction monitoring for robust quantitative proteomic analysis of cellular signaling networks

Alejandro Wolf‐Yadlin, Sampsa Hautaniemi, Douglas A. Lauffenburger et al. · Proceedings of the National Academy of Sciences · 2007 · 496 citations · Full text

Signaling Network, Molecular Biology, Multiple Reaction Monitoring +19