Proinsulin/Insulin Autoantibodies Measured With Electrochemiluminescent Assay Are the Earliest Indicator of Prediabetic Islet Autoimmunity

Liping Yu, Fran Dong, Dongmei Miao, Alexandra Fouts, Janet M. Wenzlau, Andrea K. Steck

Diabetes Care · 2013 · 76 citations · 22 references

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Abstract

This new ECL-IAA assay defines more precisely the onset of prediabetic autoimmunity and may help identify events triggering islet autoimmunity, as well as allow earlier intervention for type 1 diabetes. Nearly all young children progressing to diabetes are insulin autoantibody positive.

References

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