Innate immunity and intestinal microbiota in the development of Type 1 diabetes

Wen Li, Ruth E. Ley, Pavel Volchkov, +9

Nature

InflammationType 1DysbiosisAutoimmune DiseaseMucosal Immunology +12

Treatment with CD20-specific antibody prevents and reverses autoimmune diabetes in mice

Changyun Hu, Daniel Rodríguez‐Pinto, Wei Du, +5

Journal of Clinical Investigation

NLRP3 deficiency protects from type 1 diabetes through the regulation of chemotaxis into the pancreatic islets

Changyun Hu, Heyuan Ding, Yangyang Li, +5

Proceedings of the National Academy of Sciences

Innate immune responses regulate trypanosome parasite infection of the tsetse fly <i>Glossina morsitans morsitans</i>

Changyun Hu, Serap Aksoy

Molecular Microbiology

Maternal Antibiotic Treatment Protects Offspring from Diabetes Development in Nonobese Diabetic Mice by Generation of Tolerogenic APCs

Youjia Hu, Jian Peng, Ningwen Tai, +4

The Journal of Immunology

The Role of Toll‐Like Receptors 3 and 9 in the Development of Autoimmune Diabetes in NOD Mice

F. Susan Wong, Changyun Hu, Li Zhang, +4

Annals of the New York Academy of Sciences

Innate Immune SystemImmune RegulationImmunologyInnate ImmunityImmunotherapy +19

Combination Treatment With Anti-CD20 and Oral Anti-CD3 Prevents and Reverses Autoimmune Diabetes

Changyun Hu, Heyuan Ding, Xiaojun Zhang, +2

Diabetes

Differential expression of CCR8 in tumors versus normal tissue allows specific depletion of tumor-infiltrating T regulatory cells by GS-1811, a novel Fc-optimized anti-CCR8 antibody

Jessica D. Weaver, Edward C. Stack, Joshua Buggé, +26

OncoImmunology

T-regulatory CellImmunologyImmunoeditingRegulatory T CellsImmunologic Mechanism +18

Infections with Immunogenic Trypanosomes Reduce Tsetse Reproductive Fitness: Potential Impact of Different Parasite Strains on Vector Population Structure

Changyun Hu, Rita V. M. Rio, Jan Medlock, +8

PLoS neglected tropical diseases

FitnessEntomologyImmunologyMalariaImmune System +16

Toll-like receptor 9 negatively regulates pancreatic islet beta cell growth and function in a mouse model of type 1 diabetes

Mengju Liu, Jian Peng, Ningwen Tai, +7

Diabetologia