Effect of carbon source on the antimicrobial activity of Corynebacterium kutscheri and Corynebacterium xerosis

Abstract

In an attempt to screen out new potent antimicrobial substances producing bacteria,Corynebacterium kutscheri NB-1 and Corynebacterium xerosis NB-2 were isolated and were found antagonistic to bacteria and fungi. Antimicrobial substances production of the bacterial strains was greatly influenced by variation of carbon sources. Galactose and glucose strongly enhanced the antimicrobial activity ofCorynebacterium kutscheri and Corynebacterium xerosis, respectively. But their antimicrobial activity had been repressed by ribose and lactose, respectively.   Key words: Antimicrobial substances, Corynebacterium kutscheri, Corynebacterium xerosis, fermentation.