Concepedia

Expression of pro-apoptotic (p53, p21, bax, bak and fas) and anti-apoptotic (bcl-2 and bcl-x) proteins in serous versus mucinous borderline ovarian tumours

R. Fauvet, Charlotte Dufournet, C. Poncelet, Catherine Uzan, D. Hugol, Émile Daraï

Journal of Surgical Oncology · 2005 · 34 citations · 27 references

DOI

Abstract

Although p53 overexpression was a common feature of both mucinous and serous borderline tumours, p21 and bcl-2 overexpression appeared specific to serous tumours.

References

27

Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells

David L. Vaux, Suzanne Cory, Jerry M. Adams · Nature · 1988 · 3.2K citations

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Mice Lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

Chu‐Xia Deng, Pumin Zhang, J. Wade Harper et al. · Cell · 1995 · 2.1K citations · Full text

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Bax-Deficient Mice with Lymphoid Hyperplasia and Male Germ Cell Death

C. Michael Knudson, Kenneth S. K. Tung, Warren G. Tourtellotte et al. · Science · 1995 · 1.5K citations

Radiation-induced cell cycle arrest compromised by p21 deficiency

James Brugarolas, Chitra Chandrasekaran, Jeffrey I. Gordon et al. · Nature · 1995 · 1.2K citations

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Bax suppresses tumorigenesis and stimulates apoptosis in vivo

Chaoying Yin, C. Michael Knudson, Stanley J. Korsmeyer et al. · Nature · 1997 · 662 citations

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