Concepedia

Elevated PGC-1α Activity Sustains Mitochondrial Biogenesis and Muscle Function without Extending Survival in a Mouse Model of Inherited ALS

Sandrine Da Cruz, Philippe A. Parone, Vanda S. Lopes, Concepción Lillo, Melissa McAlonis‐Downes, Sandra K. Lee, Anne P. Vetto, Susanna Petrosyan, Martin Maršala, Anne N. Murphy,

Cell Metabolism · 2012 · 175 citations · 17 references

DOI

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References

17

Transcriptional co-activator PGC-1α drives the formation of slow-twitch muscle fibres

Jiandie D. Lin, Paul T. Tarr, Chen-Yu Zhang et al. · Nature · 2002 · 2.5K citations

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Onset and Progression in Inherited ALS Determined by Motor Neurons and Microglia

Séverine Boillée, Koji Yamanaka, Christian S. Lobsiger et al. · Science · 2006 · 1.6K citations

, , +17

Aggregation and Motor Neuron Toxicity of an ALS-Linked SOD1 Mutant Independent from Wild-Type SOD1

Lucie Bruijn, Megan K. Houseweart, Shinsuke Kato et al. · Science · 1998 · 1.2K citations

, , +17

HIF-independent regulation of VEGF and angiogenesis by the transcriptional coactivator PGC-1α

Zoltàn Arany, ShiYin Foo, Yanhong Ma et al. · Nature · 2008 · 1.1K citations · Full text

, , +14

PGC-1α protects skeletal muscle from atrophy by suppressing FoxO3 action and atrophy-specific gene transcription

Marco Sandri, Jiandie D. Lin, Christoph Handschin et al. · Proceedings of the National Academy of Sciences · 2006 · 966 citations · Full text

, , +14