Visible Spectra of Type II Cytochrome P450-Drug Complexes: Evidence that “Incomplete” Heme Coordination Is Common

[27] Measurement of substrate and inhibitor binding to microsomal cytochrome P-450 by optical-difference spectroscopy

Colin R. Jefcoate · Methods in enzymology on CD-ROM/Methods in enzymology · 1978 · 358 citations

Natural Sciences, Biochemistry, Chemistry +10

Structure of Mammalian Cytochrome P450 2B4 Complexed with 4-(4-Chlorophenyl)imidazole at 1.9-Å Resolution

Emily E. Scott, Mark A. White, You Ai He et al. · Journal of Biological Chemistry · 2004 · 284 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Effect of Antifungal Drugs on Cytochrome P450 (CYP) 2C9, CYP2C19, and CYP3A4 Activities in Human Liver Microsomes

Toshiro Niwa, Toshifumi Shiraga, Akira Takagi · Biological and Pharmaceutical Bulletin · 2005 · 271 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +17

Ligand-Induced Heme Ruffling and Bent NO Geometry in Ultra-High-Resolution Structures of Nitrophorin 4^,

Sue A. Roberts, A. Weichsel, Yan Qiu et al. · Biochemistry · 2001 · 142 citations

Life Sciences, Biochemistry, Chemistry +16

CYP2C9 Inhibition: Impact of Probe Selection and Pharmacogenetics on in Vitro Inhibition Profiles

Vikas Kumar, Jan L. Wahlstrom, Dan A. Rock et al. · Drug Metabolism and Disposition · 2006 · 132 citations

Medicine, Pharmacokinetics, Pharmacology +16