Concepedia

Phosphorylation of focal adhesion kinase on tyrosine 194 by Met leads to its activation through relief of autoinhibition

Chen Th, Chan Pc, Chen Cl, Chen Hc

Oncogene · 2010 · 36 citations · 31 references

DOI

Concepts

References

31

pp125FAK a structurally distinctive protein-tyrosine kinase associated with focal adhesions.

Michael D. Schaller, Cheryl A. Borgman, Bradley S. Cobb et al. · Proceedings of the National Academy of Sciences · 1992 · 1.4K citations

, , +17

FAK integrates growth-factor and integrin signals to promote cell migration

David J. Sieg, Christof R. Hauck, Duško Ilić et al. · Nature Cell Biology · 2000 · 1.2K citations · Full text

, , +14

Autophosphorylation of the Focal Adhesion Kinase, ppl25<sup>FAK</sup>, Directs SH2-Dependent Binding of pp60<i><sup>src</sup></i>

Michael D. Schaller, Jeffrey D. Hildebrand, John D. Shannon et al. · Molecular and Cellular Biology · 1994 · 1.1K citations · Full text

, , +17

Tyrosine Phosphorylation of Focal Adhesion Kinase at Sites in the Catalytic Domain Regulates Kinase Activity: a Role for Src Family Kinases

Mihail CALALB, Thomas R. Polte, Steven K. Hanks · Molecular and Cellular Biology · 1995 · 987 citations · Full text

, , +17

Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src.

Michael D. Schaller, Jeffrey D. Hildebrand, John D. Shannon et al. · Molecular and Cellular Biology · 1994 · 868 citations · Full text

, , +17