Morphologically Normal-Appearing Mammary Epithelial Cells Obtained from High-Risk Women Exhibit Methylation Silencing of <i>INK4a/ARF</i> - Concepedia

Concepedia

Publication | Open Access

Morphologically Normal-Appearing Mammary Epithelial Cells Obtained from High-Risk Women Exhibit Methylation Silencing of <i>INK4a/ARF</i>

DOI Full Paper Access

47

Citations

39

References

2007

Year

Gregory R. Bean, Andrew D. Bryson, Patrick G. Pilié, Vanessa Goldenberg, Joseph C. Baker, Catherine Ibarra, Danielle M. Brander, Carolyn Paisie, Natalie R. Case, Mona L. Gauthier,

Clinical Cancer Research

Abstract

Because INK4a/ARF promoter hypermethylation does not increase with age but increases with the frequency of other methylation events, we predict that INK4a/ARF promoter hypermethylation may serve as a marker of global methylation dysregulation.

References

	Year	Citations

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