Concepedia

Cytosolic Entry of Bisphosphonate Drugs Requires Acidification of Vesicles after Fluid-Phase Endocytosis

Keith Thompson, Michael J. Rogers, Fraser P. Coxon, Julie C. Crockett

Molecular Pharmacology · 2006 · 240 citations · 34 references

DOI

Concepts

References

34

Bafilomycins: a class of inhibitors of membrane ATPases from microorganisms, animal cells, and plant cells.

Emma Jean Bowman, Annette Siebers, Karlheinz Altendorf · Proceedings of the National Academy of Sciences · 1988 · 1.8K citations · Full text

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Nitrogen-Containing Bisphosphonates Inhibit the Mevalonate Pathway and Prevent Post-Translational Prenylation of GTP-Binding Proteins, Including Ras

Steven P. Luckman, D. E. Hughes, Fraser P. Coxon et al. · Journal of Bone and Mineral Research · 1998 · 1.2K citations · Full text

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Bisphosphonate action. Alendronate localization in rat bone and effects on osteoclast ultrastructure.

Masahiko Sato, W A Grasser, Naoto Endo et al. · Journal of Clinical Investigation · 1991 · 1K citations · Full text

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Structure-Activity Relationships for Inhibition of Farnesyl Diphosphate Synthase in Vitro and Inhibition of Bone Resorption in Vivo by Nitrogen-Containing Bisphosphonates

James E. Dunford, Keith Thompson, Fraser P. Coxon et al. · Journal of Pharmacology and Experimental Therapeutics · 2001 · 896 citations

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Dansylcadaverine inhibits internalization of 125I-epidermal growth factor in BALB 3T3 cells.

Harry T. Haigler, Frederick R. Maxfield, Mark C. Willingham et al. · Journal of Biological Chemistry · 1980 · 794 citations · Full text

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