Differential effects of gemcitabine on ribonucleotide pools of twenty-one solid tumour and leukaemia cell lines

Feasibility of a High-Flux Anticancer Drug Screen Using a Diverse Panel of Cultured Human Tumor Cell Lines

Anne Monks, Dominic A. Scudiero, Philip Skehan et al. · JNCI Journal of the National Cancer Institute · 1991 · 3.3K citations

Medicine, Oncology, Pharmacology +11

Action of 2',2'-difluorodeoxycytidine on DNA synthesis.

Peng Huang, Sherri Chubb, Larry W. Hertel et al. · PubMed · 1991 · 884 citations

Life Sciences, Genetics, Molecular Biology +11

Gemcitabine: metabolism, mechanisms of action, and self-potentiation.

William Plunkett, Peng Huang, Yi-Zheng Xu et al. · PubMed · 1995 · 756 citations

Life Sciences, Pharmacokinetics, Pharmacology +6

Evaluation of the antitumor activity of gemcitabine (2',2'-difluoro-2'-deoxycytidine).

Larry W. Hertel, G B Boder, Julian S. Kroin et al. · PubMed · 1990 · 683 citations

Medicine, Oncology, Pharmacology +11

Comparison of the cellular pharmacokinetics and toxicity of 2',2'-difluorodeoxycytidine and 1-beta-D-arabinofuranosylcytosine.

Volker Heinemann, Larry W. Hertel, Gerald B. Grindey et al. · PubMed · 1988 · 509 citations

Medicine, Pharmacokinetics, Pharmacology +13