The N-terminal alanine-extended GLP-1/IgG-Fc fusion protein confers resistance to DPP-IV and reduces serum glucose level in db/db mice

A Recombinant Human Glucagon-Like Peptide (GLP)-1–Albumin Protein (Albugon) Mimics Peptidergic Activation of GLP-1 Receptor–Dependent Pathways Coupled With Satiety, Gastrointestinal Motility, and Glucose Homeostasis

Laurie L. Baggio, Qingling Huang, Theodore J. Brown et al. · Diabetes · 2004 · 379 citations · Full text

Life Sciences, Endocrinology, Pharmacology +17

Dipeptidyl peptidase IV resistant analogues of glucagon-like peptide-1 which have extended metabolic stability and improved biological activity

Carolyn F. Deacon, Lotte Bjerre Knudsen, Kjeld Madsen et al. · Diabetologia · 1998 · 305 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

The Glucagon-Like Peptides

Timothy J. Kieffer · Endocrine Reviews · 1999 · 219 citations · Full text

Biological Activities of Glucagon-Like Peptide-1 Analogues in Vitro and in Vivo

Qing Xiao, Jean‐François Giguère, Michèle Parisien et al. · Biochemistry · 2001 · 106 citations

Medicine, Endocrinology, Pharmacology +17

Gene therapy of diabetes using a novel GLP-1/IgG1-Fc fusion construct normalizes glucose levels in db/db mice

M. Sunil Kumar, Yun Peng Hunag, Yelena Glinka et al. · Gene Therapy · 2006 · 69 citations

Medicine, Endocrinology, Molecular Biology +15