Addition of thiopurines can recapture response in patients with <scp>C</scp>rohn's disease who have lost response to anti‐tumor necrosis factor monotherapy

Abstract

Addition of a thiopurine in patients who have lost response to anti-TNF monotherapy is an effective strategy to recapture response even if the patient has previously failed thiopurine therapy. Thiopurines may reduce immunogenicity or act synergistically with anti-TNF therapy.