Ligand Specific Up-Regulation of a Renilla reniformis Luciferase-Tagged, Structurally Unstable Muscarinic M3 Chimeric G Protein-Coupled Receptor

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

Mark A. Bradford · Analytical Biochemistry · 1976 · 225.4K citations

Life Sciences, Biochemistry, Protein Biochemistry +7

A mutation-induced activated state of the beta 2-adrenergic receptor. Extending the ternary complex model.

Philippe Samama, Susanna Cotecchia, Tommaso Costa et al. · Journal of Biological Chemistry · 1993 · 1.3K citations · Full text

Life Sciences, Molecular Biology, Pharmacology +17

Agonists induce conformational changes in transmembrane domains III and VI of the β2 adrenoceptor

Ulrik Gether · The EMBO Journal · 1997 · 388 citations · Full text

Life Sciences, Biochemistry, Pharmacology +16

Structural Instability of a Constitutively Active G Protein-coupled Receptor

Ulrik Gether, Roland Seifert, Juan Antonio Ballesteros‐Cánovas et al. · Journal of Biological Chemistry · 1997 · 299 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

Role of Clathrin-mediated Endocytosis in Agonist-induced Down-regulation of the β2-Adrenergic Receptor

Alison W. Gagnon, Lorena A. Kallal, Jeffrey Benovic · Journal of Biological Chemistry · 1998 · 216 citations · Full text

Life Sciences, Cell Biology, Pharmacology +17