Concepedia

α-Adducin and angiotensin-converting enzyme polymorphisms in hypertension: evidence for a joint influence on albuminuria

Roberto Pedrinelli, Giulia Dell’Omo, Giuseppe Penno, Vitantonio Di Bello, Laura Pucci, Carmen Fotino, Daniela Lucchesi, Stefano Del Prato, Chiara Dal Fiume, Cristina Barlassina,

Journal of Hypertension · 2006 · 19 citations · 32 references

DOI

Abstract

ACE DD and ADD1 Gly460Gly polymorphisms may jointly influence albuminuria in hypertensive men, 460Gly homozygosis facilitating or, possibly, the 460Trp allele mitigating the noxious renal impact of the ACE DD genotype. The data highlight further the complex pathophysiological implications of microalbuminuria in hypertension.

References

32

Prediction of Creatinine Clearance from Serum Creatinine

Donald W. Cockcroft, Henry Gault · Nephron · 1976 · 15.3K citations

An insertion/deletion polymorphism in the angiotensin I-converting enzyme gene accounting for half the variance of serum enzyme levels.

Brigitte Rigat, C. Hübert, F Alhenc‐Gelas et al. · Journal of Clinical Investigation · 1990 · 3.8K citations · Full text

, , +20

A general method for isolation of high molecular weight DNA from eukaryotes

Nikolaus Blin, Darrel W. Stafford · Nucleic Acids Research · 1976 · 2.8K citations · Full text

Association of the Renin-Sodium Profile with the Risk of Myocardial Infarction in Patients with Hypertension

M. H. Alderman, Shantha Madhavan, Wee Lock Ooi et al. · New England Journal of Medicine · 1991 · 733 citations · Full text

Evidence for Association and Genetic Linkage of the Angiotensin-Converting Enzyme Locus With Hypertension and Blood Pressure in Men but Not Women in the Framingham Heart Study

Christopher J. O’Donnell, Klaus Lindpaintner, Martin G. Larson et al. · Circulation · 1998 · 553 citations · Full text