Concepedia

Asymmetric dihydroxylation of aryl olefins by sequential enantioselective epoxidation and regioselective hydrolysis with tandem biocatalysts

Yi Xu, Xin Jia, Sven Panke, Zhi Li

Chemical Communications · 2009 · 60 citations · 14 references

DOI

Abstract

Chiral aryl vicinal diols were obtained in high ee and yield by asymmetric dihydroxylation of aryl olefins with tandem biocatalysts: one contains an enantioselective styrene monooxygenase, and the other contains a regioselective epoxide hydrolase.

References

14

Deracemization of Secondary Alcohols through a Concurrent Tandem Biocatalytic Oxidation and Reduction

Constance V. Voss, Christian Gruber, Wolfgang Kroutil · Angewandte Chemie International Edition · 2007 · 155 citations

, , +17

Integrated Biocatalytic Synthesis on Gram Scale: The Highly Enantioselective Preparation of Chiral Oxiranes with Styrene Monooxygenase

Andreas Schmid, Karin Hofstetter, Hans-Jürgen Feiten et al. · Advanced Synthesis & Catalysis · 2001 · 129 citations

, , +16

Engineering of a Stable Whole-Cell Biocatalyst Capable of ( <i>S</i> )-Styrene Oxide Formation for Continuous Two-Liquid-Phase Applications

Sven Panke, Vı́ctor de Lorenzo, Arnë Kaiser et al. · Applied and Environmental Microbiology · 1999 · 95 citations · Full text

, , +17

Biocatalytic Asymmetric Dihydroxylation of Conjugated Mono‐ and Poly‐alkenes to Yield Enantiopure Cyclic <i>cis</i>‐Diols

Derek R. Boyd, Narain D. Sharma, Nigel I. Bowers et al. · Advanced Synthesis & Catalysis · 2005 · 56 citations · Full text

, , +14

Stereospecific dihydroxylation of the styrene vinyl group by purified naphthalene dioxygenase from Pseudomonas sp. strain NCIB 9816-4

K Lee, David T. Gibson · Journal of Bacteriology · 1996 · 52 citations · Full text

, , +18