Publication | Closed Access
Discovery and identification of Cdc37-derived peptides targeting the Hsp90–Cdc37 protein–protein interaction
24
Citations
36
References
2015
Year
Molecular DockingProtein FunctionEngineeringBiochemistryNatural SciencesPeptide LibraryMolecular BiologyProtein ModelingMolecular SimulationCdc37-derived PeptidesMm-pbsa AnalysisSystems BiologyProteomicsMolecular ModelingProtein BioinformaticsPeptide InhibitorsHsp90–cdc37 Protein–protein InteractionHsp90–cdc37 Binding Interface
In order to explore the key residues of the Hsp90–Cdc37 binding interface for further design of peptide inhibitors, a combined strategy of molecular dynamics simulation and MM-PBSA analysis was performed.
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