Differential Regulation and Relocalization of the Platelet P2Y Receptors after Activation: A Way to Avoid Loss of Hemostatic Properties?

Identification of the platelet ADP receptor targeted by antithrombotic drugs

Gunther Hollopeter, Hans‐Michael Jantzen, D Vincent et al. · Nature · 2001 · 1.4K citations

Medicine, Hematology, Pharmacology +14

Targeted disruption of cd39/ATP diphosphohydrolase results in disordered hemostasis and thromboregulation

Keiichi Enjyoji, Jean Sévigny, Yuan Lin et al. · Nature Medicine · 1999 · 575 citations

Medicine, Biochemistry, Molecular Biology +12

Defective platelet aggregation and increased resistance to thrombosis in purinergic P2Y1 receptor–null mice

Catherine Léon, Béatrice Hechler, Monique Freund et al. · Journal of Clinical Investigation · 1999 · 454 citations · Full text

Medicine, Cell Biology, Pharmacology +17

Decreased platelet aggregation, increased bleeding time and resistance to thromboembolism in P2Y1-deficient mice

Jean-Etienne Fabre, MyTrang Nguyen, Anne M. Latour et al. · Nature Medicine · 1999 · 440 citations

Medicine, Cell Biology, Hematology +16

Isolation and Characterization of Plasma Membranes from Human Blood Platelets

Alfred J. Barber, Graham Jamieson · Journal of Biological Chemistry · 1970 · 428 citations · Full text

Life Sciences, Biochemistry, Cell Biology +16