K-Estimator: calculation of the number of nucleotide substitutions per site and the confidence intervals

Abstract

UNLABELLED: K-Estimator 4.5 is a Windows program that estimates the number of nucleotide substitutions per site (divergence) when comparing two aligned nucleotide sequences, both protein-coding and non-coding. Confidence intervals of the divergence estimates are obtained by Monte Carlo simulation. AVAILABILITY: The program is available for non-profit use via anonymous ftp at ftp.bio.indiana. edu/molbio/mswin. CONTACT: jcomeron@midway.uchicago.edu