Concepedia

Base Substitutions

Base Substitutions is a type of point mutation in which a single nucleotide base is replaced by a different nucleotide base in the DNA sequence, altering the genetic information at a specific locus.

3.4K

Publications

273K

Citations

14.5K

Authors

2.7K

Institutions

Publications per year

2017–2026

351

Variants

Nucleotide Substitutions

Parents

Publications

3.4K

A simple method for estimating evolutionary rates of base substitutions through comparative studies of nucleotide sequences

Journal of Molecular Evolution · 1980 · 29.8K citations

, , +15

PAL2NAL: robust conversion of protein sequence alignments into the corresponding codon alignments

Mikita Suyama, David Torrents, Peer Bork · Nucleic Acids Research · 2006 · 3.6K citations · Full text

, , +15

Rapid phylogenetic analysis of large samples of recombinant bacterial whole genome sequences using Gubbins

Nicholas J. Croucher, Andrew J. Page, Thomas R. Connor et al. · Nucleic Acids Research · 2014 · 2.9K citations · Full text

, , +17

THE NUMBER OF ALLELES THAT CAN BE MAINTAINED IN A FINITE POPULATION

James F. Crow · Genetics · 1964 · 2.7K citations

, , +12

Human Gene Mutation Database (HGMD<sup>®</sup>): 2003 update

Peter D. Stenson, Edward V. Ball, Matthew Mort et al. · Human Mutation · 2003 · 1.9K citations

, , +15

1–5 of 3.4K

Authors

14.5K

  1. TA
    Thomas A. Kunkel

    National Institute of Environmental Health Sciences, United States

    18 publications · 2.7K citations

    18

    h-index

  2. DC
    D.N. Cooper

    Cardiff University, United Kingdom

    19 publications · 5K citations

    18

    h-index

  3. LA
    Lawrence A. Loeb

    University of Washington, United States

    17 publications · 3.1K citations

    15

    h-index

  4. BW
    Barry W. Glickman

    University of Victoria, Canada

    16 publications · 995 citations

    13

    h-index

  5. TM
    Tom Maniatis

    Harvard University, United States

    11 publications · 3K citations

    11

    h-index

1–5 of 14.5K

Institutions

2.7K

  1. National Institutes of Health

    Bethesda, United States

    47 h-index

    279 publications

    24.9K citations

  2. Harvard University

    Cambridge, United States

    45 h-index

    173 publications

    22.2K citations

  3. Howard Hughes Medical Institute

    Chevy Chase, United States

    35 h-index

    115 publications

    14.3K citations

  4. Centre National de la Recherche Scientifique

    Paris, France

    35 h-index

    213 publications

    11.7K citations

  5. University of Washington

    Seattle, United States

    32 h-index

    152 publications

    16.6K citations

  6. National Institute of Environmental Health Sciences

    Durham, United States

    28 h-index

    99 publications

    9.4K citations

  7. Kyoto University

    Kyoto, Japan

    27 h-index

    133 publications

    7.4K citations

  8. Cornell University

    Ithaca, United States

    27 h-index

    94 publications

    6.7K citations

1–8 of 2.7K

Venues

  1. Proceedings of the National Academy of Sciences

    PNAS · 225 publications · 29.3K citations

    102

    h-index

  2. Journal of Virology

    JVI · 138 publications · 11.9K citations

    67

    h-index

  3. Journal of Biological Chemistry

    JBC · 159 publications · 12.3K citations

    60

    h-index

  4. Nucleic Acids Research

    189 publications · 17.8K citations

    59

    h-index

  5. Molecular Biology and Evolution

    MBE · 99 publications · 9K citations

    53

    h-index

1–5