Efficacy Studies on Meticlorpindol as a Coccidiostat

Abstract

NINETEEN or more coccidiostats have been manufactured and marketed in the United States to mix in poultry feeds for prevention of coccidiosis (Reid, 1961). Such materials are so commonly accepted that chick starter feed minus a coccidiostat is mixed only on special order by most commercial feed companies. This new class of additives has introduced many new problems for feed manufacturers who have become increasingly more demanding in specifications for new coccidiostats (Edgar, 1958). Some of the different properties listed for an ideal coccidiostat include good mixing properties, easy methods of chemical detection, nontoxic properties, low cost and an increasing demand for efficacy against the less known intestinal species of coccidia. Increasing evidence of development in coccidia of resistance to coccidiostats has come both from laboratory studies (Waletzky et al., 1954; Pellerdy, 1962; Vegh, 1962) and from feeding experiments (Cuckler and Malenga, 1955; Joyner, 1957; McLoughlin and Gardiner, 1961, 1962; …