Laterally Spreading Type of Colorectal Adenoma Exhibits a Unique Methylation Phenotype and K-ras Mutations

Genetic Alterations during Colorectal-Tumor Development

Bert Vogelstein, Eric R. Fearon, Stanley R. Hamilton et al. · New England Journal of Medicine · 1988 · 6.8K citations

Medicine, Genetics, Oncology +14

Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands.

James G. Herman, Jeremy R. Graff, Sanna Myöhänen et al. · Proceedings of the National Academy of Sciences · 1996 · 5.7K citations

Life Sciences, Genetics, Molecular Biology +17

CpG island methylator phenotype in colorectal cancer

Minoru Toyota, Nita Ahuja, Mutsumi Ohe-Toyota et al. · Proceedings of the National Academy of Sciences · 1999 · 2.5K citations

Medicine, Genetics, Oncology +17

Hypomethylation distinguishes genes of some human cancers from their normal counterparts

Andrew P. Feinberg, Bert Vogelstein · Nature · 1983 · 2.4K citations

Medicine, Genetics, Molecular Genetics +13

Alterations in DNA Methylation: A Fundamental Aspect of Neoplasia

Stephen B. Baylln, James G. Herman, Jeremy R. Graff et al. · Advances in cancer research · 1997 · 1.9K citations

Medicine, Genetics, Oncology +14