Concepedia

G-CSF regulates hematopoietic stem cell activity, in part, through activation of Toll-like receptor signaling

Laura G. Schuettpelz, Joshua N. Borgerding, Matt Christopher, Priya Gopalan, Molly Romine, Angela Herman, Jill Woloszynek, Adam Greenbaum, Daniel C. Link

Leukemia · 2014 · 136 citations · 44 references

DOI

Concepts

References

44

Hematopoietic Stem Cells Reversibly Switch from Dormancy to Self-Renewal during Homeostasis and Repair

Anne Wilson, Elisa Laurenti, Gabriela Oser et al. · Cell · 2008 · 1.9K citations · Full text

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IFNα activates dormant haematopoietic stem cells in vivo

Marieke Essers, Sandra Offner, William Blanco-Bose et al. · Nature · 2009 · 1.4K citations · Full text

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G-CSF induces stem cell mobilization by decreasing bone marrow SDF-1 and up-regulating CXCR4

Isabelle Petit, Martine Szyper‐Kravitz, Arnon Nagler et al. · Nature Immunology · 2002 · 1.3K citations

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Toll-like Receptors on Hematopoietic Progenitor Cells Stimulate Innate Immune System Replenishment

Yoshinori Nagai, Karla P. Garrett, Shoichiro Ohta et al. · Immunity · 2006 · 838 citations · Full text

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Disruption of the CXCR4/CXCL12 chemotactic interaction during hematopoietic stem cell mobilization induced by GCSF or cyclophosphamide

Jean-Pierre Lévesque, Jean Hendy, Yasushi Takamatsu et al. · Journal of Clinical Investigation · 2003 · 748 citations · Full text

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