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The NADPH oxidase inhibitor DPI can abolish hypoxia-induced apoptosis of human kidney proximal tubular epithelial cells through Bcl2 up-regulation via ERK activation without ROS reduction

Reductive StressCell SignalingMedicineApoptosisChronic Kidney DiseaseLipid PeroxidationCell DeathErk ActivationRos ReductionReactive Oxygen SpeciePharmacologyCell BiologyRedox BiologyNephrologyHypoxia-induced ApoptosisOxidative Stress