The Usability of Allele-Specific PCR and Reverse-Hybridization Assays for KRAS Genotyping in Serbian Colorectal Cancer Patients

Genetic Alterations during Colorectal-Tumor Development

Bert Vogelstein, Eric R. Fearon, Stanley R. Hamilton et al. · New England Journal of Medicine · 1988 · 6.8K citations

Medicine, Genetics, Oncology +14

Kisten ras mutations in patients with colorectal cancer: the “RASCAL II” study.

David Cunningham, J. Oates, Joanne Young et al. · IRIS UNIMORE (University of Modena and Reggio Emilia) · 2001 · 890 citations · Full text

Medicine, Genetics, Oncology +12

Oncogenic Activation of the RAS/RAF Signaling Pathway Impairs the Response of Metastatic Colorectal Cancers to Anti–Epidermal Growth Factor Receptor Antibody Therapies

Silvia Benvenuti, Andrea Sartore‐Bianchi, Federica Di Nicolantonio et al. · Cancer Research · 2007 · 830 citations · Full text

Medicine, Cancer Biology, Oncology +16

KRAS wild-type state predicts survival and is associated to early radiological response in metastatic colorectal cancer treated with cetuximab

Wendy De Roock, Hubert Piessevaux, Joris De Schutter et al. · Annals of Oncology · 2007 · 827 citations · Full text

Medicine, Oncology, Radiology +12

Association of KRAS p.G13D Mutation With Outcome in Patients With Chemotherapy-Refractory Metastatic Colorectal Cancer Treated With Cetuximab

Wendy De Roock, Derek J. Jonker, Federica Di Nicolantonio et al. · JAMA · 2010 · 747 citations

Medicine, Oncology, Pharmacology +17