Concepedia

Nrf2 is an inhibitor of the Fas pathway as identified by Achilles' Heel Method, a new function-based approach to gene identification in human cells

Kumar Kotlo, Furma Yehiely, Elena V. Efimova, Heather Harasty, Bahar Hesabi, Ksenya Shchors, Paz Einat, Ada Rozen, Eva Berent, Louis P. Deiss

Oncogene · 2003 · 76 citations · 32 references

DOI

Concepts

References

32

An Nrf2/Small Maf Heterodimer Mediates the Induction of Phase II Detoxifying Enzyme Genes through Antioxidant Response Elements

Ken Itoh, Tomoki Chiba, Satoru Takahashi et al. · Biochemical and Biophysical Research Communications · 1997 · 4K citations

, , +14

Two CD95 (APO‐1/Fas) signaling pathways

Carsten Scaffidi · The EMBO Journal · 1998 · 3K citations · Full text

, , +12

In Vivo Protein Transduction: Delivery of a Biologically Active Protein into the Mouse

Steven R. Schwarze, Alan L. Ho, Adamina Vocero-Akbani et al. · Science · 1999 · 2.4K citations

, , +15

Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the beta-globin locus control region.

Paolo Moi, Isadora Asunis, Antonio Cao et al. · Proceedings of the National Academy of Sciences · 1994 · 1.6K citations

, , +17

Transcription Factor Nrf2 Coordinately Regulates a Group of Oxidative Stress-inducible Genes in Macrophages

Tetsuro Ishii, Ken Itoh, Satoru Takahashi et al. · Journal of Biological Chemistry · 2000 · 1.5K citations · Full text

, , +17