Reverse transcriptase-dependent synthesis of a covalently linked, branched DNA-RNA compound in E. coli B

DNA sequencing with chain-terminating inhibitors

Frederick Sanger, S. Nicklen, Alan Coulson · Proceedings of the National Academy of Sciences · 1977 · 69.1K citations · Full text

Dna, Engineering, Dna Analysis +20

Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mpl8 and pUC19 vectors

Celeste Yanisch-Perron, Jeffrey Vieira, Joachim Messing · Gene · 1985 · 15.1K citations

Genetics, Puc19 Vectors, Bacteriophage +9

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

Allan M. Maxam, Walter Gilbert · Methods in enzymology on CD-ROM/Methods in enzymology · 1980 · 14.7K citations

Dna Sequencing, Nucleic Acid Chemistry, Dna +3

A comprehensive set of sequence analysis programs for the VAX

John Devereux, Paul Haeberli, Oliver Smithies · Nucleic Acids Research · 1984 · 14.4K citations · Full text

Unidirectional digestion with exonuclease III creates targeted breakpoints for DNA sequencing

Steven Henikoff · Gene · 1984 · 4.2K citations

Long-read Sequencing, Dna Sequencing, Next-generation Sequencing +11