On the Hydrazinolysis of Proteins and Peptides: A Method for the Characterization of Carboxyl-terminal Amino Acids in Proteins

Shiro Akabori, Ko Ohno, Kozo Narita

Bulletin of the Chemical Society of Japan · 1952 · 382 citations · 4 references

Concepts

Abstract

Abstract (1) A brief method for the characterization of carboxyl-terminal amino acids in peptides and proteins was investigated. (2) Several new amino acid hydrazides were synthesized. (3) Soveral di- and tri-peptides were hydrazinolyzed and identified their carboxylterminal amino acid. (4) The method was applied to beef insulin and tyrocidin for the demonstration of its applicability.

References

4