Concepedia

Deramciclane, a putative anxiolytic drug, is a serotonin 5-HT 2C receptor inverse agonist but fails to induce 5-HT 2C receptor down-regulation

Esa-Pekka Pälvimäki, Hannu Majasuo, Mikko Kuoppamäki, Pekka T. Männistö, Erkka Syvälahti, Jarmo Hietala

Psychopharmacology · 1998 · 31 citations · 22 references

DOI

Concepts

References

22

Long-Term Antidepressant Treatment Decreases Spiroperidol-Labeled Serotonin Receptor Binding

Stephen J. Peroutka, Solomon H. Snyder · Science · 1980 · 838 citations

, , +17

A constitutively activating mutation of the luteinizing hormone receptor in familial male precocious puberty

Andrew Shenker, Louisa Laue, Shinji Kosugi et al. · Nature · 1993 · 756 citations · Full text

, , +14

Inverse agonism: pharmacological curiosity or potential therapeutic strategy?

Graeme Milligan, Richard A. Bond, Melanie Lee · Trends in Pharmacological Sciences · 1995 · 294 citations

, , +13

Anxiogenic-like effects of mCPP and TFMPP in animal models are opposed by 5-HT1C receptor antagonists

G.A. Kennett, Peter S. Whitton, K. Shah et al. · European Journal of Pharmacology · 1989 · 283 citations

, , +4

Tissue Concentrations of Clozapine and its Metabolites in the Rat

Ross J. Baldessarini, Franca Centorrino, James G. Flood et al. · Neuropsychopharmacology · 1993 · 232 citations

, , +11