Inverse agonism: pharmacological curiosity or potential therapeutic strategy?

Graeme Milligan, Richard A. Bond, Melanie Lee

Trends in Pharmacological Sciences

Pharmacological StudyFunctional SelectivityPharmacologyInverse AgonismPharmacotherapy +2

A Bioluminescent Assay for Agonist Activity at Potentially Any G-Protein-Coupled Receptor

Jenny Stables, Andrew R. Green, Fiona H. Marshall, +6

Analytical Biochemistry

Molecular PharmacologyMolecular PhysiologySignal TransductionBiochemistryBioluminescent Assay +8

Direct Regulation of the Microphthalmia Promoter by Sox10 Links Waardenburg-Shah Syndrome (WS4)-associated Hypopigmentation and Deafness to WS2

Melanie Lee, Jane Goodall, Carole Verastegui, +2

Journal of Biological Chemistry

Cloning and characterisation of the human 5‐HT_5A serotonin receptor

Stephen Edward Rees, Izaak den Daas, Steven M. Foord, +4

FEBS Letters

Hydrophobicity of Residue³⁵¹ of the G Protein G_i₁α Determines the Extent of Activation by the α_2A-Adrenoceptor

Alan Wise, Francesca Fanelli, Melanie Lee, +2

Biochemistry

Melatonin inhibits cell proliferation and induces caspase activation and apoptosis in human malignant lymphoid cell lines

Marina Sánchéz‐Hidalgo, Melanie Lee, Catalina Alarcón‐de‐la‐Lastra, +2

Journal of Pineal Research

Chemoprevention StrategyMelatonin InhibitsApoptosisImmunologyCell Death +16

Interactions of the α2A-adrenoceptor with multiple Gi-family G-proteins: studies with pertussis toxin-resistant G-protein mutants

Alan Wise, Marie-Ange WATSON-KOKEN, Stephen Edward Rees, +2

Biochemical Journal

Development of low mass-transfer-resistance fluorinated TiO 2 -SiO 2 /PVDF composite hollow fiber membrane used for biogas upgrading in gas-liquid membrane contactor

Yilin Xu, Yuqing Lin, Melanie Lee, +2

Journal of Membrane Science

Chemical EngineeringMembrane TechnologyEngineeringBiogas UpgradingTio 2 +3

Comparative Analysis of the Efficacy of A₁ Adenosine Receptor Activation of G_i_/_oα G Proteins following Coexpression of Receptor and G Protein and Expression of A₁ Adenosine Receptor−G_i_/_oα Fusion Proteins

Alan Wise, Michael J. Sheehan, Stephen Edward Rees, +2

Biochemistry

Molecular PharmacologySignal TransductionMolecular PhysiologyBiochemistryG Protein-coupled Receptor +13

Regulated Displacement of TBP from the PHO8 Promoter In Vivo Requires Cbf1 and the Isw1 Chromatin Remodeling Complex

Jean-Luc Moreau, Melanie Lee, Nyasha Mahachi, +4

Molecular Cell

Pho8 PromoterChromatinTranscriptional RegulationChromatin StructureChromatin Remodeling +10