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Organoiridium catalysed hydrogen isotope exchange of benzamide derivatives

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2001

Year

Abstract

Abstract Hydrogen‐tritium exchange in a series of benzamide derivatives and acetanilide has been investigated using [Ir(cod)(Cy 3 P)(Py)]PF 6 as catalyst. Specific activities of 6–43 Ci/mmol were obtained. Tritium NMR spectroscopy showed that exchange occurred ortho to the amide group. Copyright © 2001 John Wiley & Sons, Ltd.

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