David Hesk

Photoredox-catalyzed deuteration and tritiation of pharmaceutical compounds

Yong Yao Loh, Kazunori Nagao, Andrew J. Hoover et al. · Science · 2017 · 543 citations · Full text

Iron-catalysed tritiation of pharmaceuticals

Renyuan Pony Yu, David Hesk, Nelo R. Rivera et al. · Nature · 2016 · 416 citations

Medicinal Chemistry, Iron Metabolism, Natural Sciences +3

SCH 503034, a Mechanism-Based Inhibitor of Hepatitis C Virus NS3 Protease, Suppresses Polyprotein Maturation and Enhances the Antiviral Activity of Alpha Interferon in Replicon Cells

Bruce A. Malcolm, R. Liu, Frederick Lahser et al. · Antimicrobial Agents and Chemotherapy · 2006 · 316 citations · Full text

Viral Replication, Hepatitis C Virus, Immunology +17

Preclinical Characterization of¹⁸F-MK-6240, a Promising PET Tracer for In Vivo Quantification of Human Neurofibrillary Tangles

Eric D. Hostetler, Abbas Walji, Zhizhen Zeng et al. · Journal of Nuclear Medicine · 2016 · 278 citations · Full text

A General Strategy for Site-Selective Incorporation of Deuterium and Tritium into Pyridines, Diazines, and Pharmaceuticals

J. Luke Koniarczyk, David Hesk, Alix Overgard et al. · Journal of the American Chemical Society · 2018 · 183 citations

Organic Molecules, Chemical Engineering, Medicinal Chemistry +15