Salicylanilide derivatives block Mycobacterium tuberculosis through inhibition of isocitrate lyase and methionine aminopeptidase

Persistence of Mycobacterium tuberculosis in macrophages and mice requires the glyoxylate shunt enzyme isocitrate lyase

John D. McKinney, Kerstin Höner zu Bentrup, Ernesto J. Muñoz‐Elías et al. · Nature · 2000 · 1.3K citations · Full text

Medical Microbiology, Pulmonary Tuberculosis, Biochemistry +7

Mycobacterium tuberculosis isocitrate lyases 1 and 2 are jointly required for in vivo growth and virulence

Ernesto J. Muñoz‐Elías, John D. McKinney · Nature Medicine · 2005 · 747 citations · Full text

Medical Microbiology, Pulmonary Tuberculosis, Vivo Growth +9

Structure of isocitrate lyase, a persistence factor of Mycobacterium tuberculosis.

Vivek Sharma, Sujata Sharma, K. Hoener zu Bentrup et al. · Nature Structural Biology · 2000 · 246 citations · Full text

Biochemistry, Natural Sciences, Mycobacterium Tuberculosis +7

Novel isatinyl thiosemicarbazones derivatives as potential molecule to combat HIV-TB co-infection

Debjani Banerjee, Perumal Yogeeswari, Pritesh Bhat et al. · European Journal of Medicinal Chemistry · 2010 · 131 citations · Full text

Medicinal Chemistry, Hiv-tb Co-infection, Medicine +9

Methionine Aminopeptidases from Mycobacterium tuberculosis as Novel Antimycobacterial Targets

Omonike A. Olaleye, Tirumalai R. Raghunand, Shridhar Bhat et al. · Chemistry & Biology · 2010 · 65 citations · Full text