Concepedia

Minocycline protects against myocardial ischemia and reperfusion injury by inhibiting high mobility group box 1 protein in rats

Xiaorong Hu, Xiaoya Zhou, Bo He, Changwu Xu, Wu Liu, Bo Cui, Huazhi Wen, Zhibing Lu, Hong Jiang

European Journal of Pharmacology · 2010 · 97 citations · 18 references

DOI

Concepts

References

18

Release of chromatin protein HMGB1 by necrotic cells triggers inflammation

Paola Scaffidi, Tom Misteli, Marco E. Bianchi · Nature · 2002 · 4.2K citations

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HMG-1 as a Late Mediator of Endotoxin Lethality in Mice

Haichao Wang, Ona Bloom, Minghuang Zhang et al. · Science · 1999 · 3.4K citations

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High Mobility Group 1 Protein (Hmg-1) Stimulates Proinflammatory Cytokine Synthesis in Human Monocytes

Haichao Wang, Karin Palmblad, Ann-Charlotte Aveberger et al. · The Journal of Experimental Medicine · 2000 · 1.4K citations · Full text

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HMGB1 release induced by liver ischemia involves Toll-like receptor 4–dependent reactive oxygen species production and calcium-mediated signaling

Allan Tsung, John R. Klune, Xianghong Zhang et al. · The Journal of Experimental Medicine · 2007 · 612 citations · Full text

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High-Mobility Group Box-1 in Ischemia-Reperfusion Injury of the Heart

Martin Andrassy, H. Christian Volz, John C. Igwe et al. · Circulation · 2008 · 608 citations

, , +14