Concepedia

New 7-arylpiperazinylalkyl-8-morpholin-4-yl-purine-2,6-dione derivatives with anxiolytic activity – Synthesis, crystal structure and structure–activity study

Grażyna Chłoń‐Rzepa, Paweł Żmudzki, Maciej Pawłowski, Anna Wesołowska, Grzegorz Satała, Andrzej J. Bojarski, Mateusz Jabłoński, Justyna Kalinowska‐Tłuścik

Journal of Molecular Structure · 2014 · 13 citations · 26 references

Open access

Concepts

PharmacyMedicinal ChemistryPharmacologyDrug DiscoveryOrganic ChemistryStructure-activity RelationshipsLead Compound DesignLigand-based DesignNatural Product Drug DiscoveryPotency OptimizationStructure-activity Relationship AnalysisChemical Synthesis Of AnaloguesCrystal Structure RefinementMedicinal Chemistry ApplicationsPurine ChemistryStructure - Activity Relationship MappingStructure - Activity Relationship Optimization

References

26

A short history of<i>SHELX</i>

George M. Sheldrick · Acta Crystallographica Section A Foundations of Crystallography · 2007 · 87.4K citations · Full text

Natural Sciences, Biophysics, Chemistry +16

[20] Processing of X-ray diffraction data collected in oscillation mode

Zbyszek Otwinowski, W. Minor · Methods in enzymology on CD-ROM/Methods in enzymology · 1997 · 33.6K citations

Natural Sciences, Materials Science, Physics +12

<i>ORTEP</i>-3 for Windows - a version of<i>ORTEP</i>-III with a Graphical User Interface (GUI)

Louis J. Farrugia · Journal of Applied Crystallography · 1997 · 19.9K citations

Natural Sciences, Computer Science, Computational Chemistry +16

<i>WinGX</i>suite for small-molecule single-crystal crystallography

Louis J. Farrugia · Journal of Applied Crystallography · 1999 · 18.9K citations

Natural Sciences, Chemistry, Computational Chemistry +11

The PyMOL Molecular Graphics System

Warren L. DeLano · Medical Entomology and Zoology · 2002 · 18.1K citations

Life Sciences, Biology, Computational Biology +11