Concepedia

Author

Grażyna Chłoń‐Rzepa

Jagiellonian UniversityORCID

Also Known As

Chłoń-Rzepa, Grażyna, G CHLON, G Chloń, G Chłoń, G Chłoń-Rzepa, Grazyna Chlon, Grazyna Chlon-Rzepa, Grazyna Chłon-Rzepa, Grazyna Chłoń-Rzepa, GraŻyna Chłoń-Rzepa

78

Publications

780

Citations

16

H-Index

29

Concepts

All Affiliations

Jagiellonian UniversityMedicinaPolish Academy of SciencesMaj Institute of PharmacologyUniversity of Groningen
GC

About

Grażyna Chłoń‐Rzepa is an author at Jagiellonian University specializing in medicine, drug discovery, and pharmacology.

Top Concepts

#ConceptH-IndexPublicationsCitations

1

Medicine

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2

Biochemistry

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191

3

Natural Sciences

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6

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4

Biomolecular Engineering

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2

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5

Health Sciences

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36

Grażyna Chłoń‐Rzepa

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23

Publications

488

Citations

14

H-Index

YearCitations

A Novel, Pan-PDE Inhibitor Exerts Anti-Fibrotic Effects in Human Lung Fibroblasts via Inhibition of TGF-β Signaling and Activation of cAMP/PKA Signaling

Katarzyna Wójcik‐Pszczoła, Grażyna Chłoń‐Rzepa, Agnieszka Jankowska,

International Journal of Molecular Sciences

2020

48

Novel butanehydrazide derivatives of purine-2,6-dione as dual PDE4/7 inhibitors with potential anti-inflammatory activity: Design, synthesis and biological evaluation

Grażyna Chłoń‐Rzepa, Agnieszka Jankowska, Marietta Ślusarczyk,

European Journal of Medicinal Chemistry

2018

46

Antidepressant- and anxiolytic-like activity of 7-phenylpiperazinylalkyl-1,3-dimethyl-purine-2,6-dione derivatives with diversified 5-HT1A receptor functional profile

Anna Partyka, Grażyna Chłoń‐Rzepa, A Wasik,

Bioorganic & Medicinal Chemistry

2014

41

Novel amide derivatives of 1,3-dimethyl-2,6-dioxopurin-7-yl-alkylcarboxylic acids as multifunctional TRPA1 antagonists and PDE4/7 inhibitors: A new approach for the treatment of pain

Grażyna Chłoń‐Rzepa, Marietta Ślusarczyk, Agnieszka Jankowska,

European Journal of Medicinal Chemistry

2018

36

Synthesis, 5-HT1A and 5-HT2A receptor affinity of new 1-phenylpiperazinylpropyl derivatives of purine-2,6- and pyrrolidine-2,5-diones

Maciej Pawłowski, Grażyna Chłoń‐Rzepa, Jolanta Obniska,

Il Farmaco

2000

29

Novel anilide and benzylamide derivatives of arylpiperazinylalkanoic acids as 5-HT1A/5-HT7 receptor antagonists and phosphodiesterase 4/7 inhibitors with procognitive and antidepressant activity

Agnieszka Jankowska, Grzegorz Satała, Marcin Kołaczkowski,

European Journal of Medicinal Chemistry

2020

27

New imidazopyridines with phosphodiesterase 4 and 7 inhibitory activity and their efficacy in animal models of inflammatory and autoimmune diseases

Veronika Ručilová, Artur Świerczek, David Vanda,

European Journal of Medicinal Chemistry

2020

25

7-Arylpiperazinylalkyl and 7-tetrahydroisoquinolinylalkyl derivatives of 8-alkoxy-purine-2,6-dione and some of their purine-2,6,8-trione analogs as 5-HT1A, 5-HT2A, and 5-HT7 serotonin receptor ligands

Grażyna Chłoń‐Rzepa, Paweł Żmudzki, Paweł Zajdel,

Bioorganic & Medicinal Chemistry

2007

23

Novel phosphodiesterases inhibitors from the group of purine-2,6-dione derivatives as potent modulators of airway smooth muscle cell remodelling

Katarzyna Wójcik‐Pszczoła, Grażyna Chłoń‐Rzepa, Agnieszka Jankowska,

European Journal of Pharmacology

2019

20

New 8-aminoalkyl derivatives of purine-2,6-dione with arylalkyl, allyl or propynyl substituents in position 7, their 5-HT1A, 5-HT2A, and 5-HT7 receptor affinity and pharmacological evaluation

Grażyna Chłoń‐Rzepa, Paweł Żmudzki, Grzegorz Satała,

Pharmacological Reports

2013

19

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