Grażyna Chłoń‐Rzepa

A Novel, Pan-PDE Inhibitor Exerts Anti-Fibrotic Effects in Human Lung Fibroblasts via Inhibition of TGF-β Signaling and Activation of cAMP/PKA Signaling

Katarzyna Wójcik‐Pszczoła, Grażyna Chłoń‐Rzepa, Agnieszka Jankowska et al. · International Journal of Molecular Sciences · 2020 · 48 citations · Full text

Novel butanehydrazide derivatives of purine-2,6-dione as dual PDE4/7 inhibitors with potential anti-inflammatory activity: Design, synthesis and biological evaluation

Grażyna Chłoń‐Rzepa, Agnieszka Jankowska, Marietta Ślusarczyk et al. · European Journal of Medicinal Chemistry · 2018 · 46 citations · Full text

Medicinal Chemistry, Anti-inflammatory, Biochemistry +9

Antidepressant- and anxiolytic-like activity of 7-phenylpiperazinylalkyl-1,3-dimethyl-purine-2,6-dione derivatives with diversified 5-HT1A receptor functional profile

Anna Partyka, Grażyna Chłoń‐Rzepa, A Wasik et al. · Bioorganic & Medicinal Chemistry · 2014 · 41 citations · Full text

Anxiolytic-like Activity, Biochemistry, Functional Selectivity +8

Novel amide derivatives of 1,3-dimethyl-2,6-dioxopurin-7-yl-alkylcarboxylic acids as multifunctional TRPA1 antagonists and PDE4/7 inhibitors: A new approach for the treatment of pain

Grażyna Chłoń‐Rzepa, Marietta Ślusarczyk, Agnieszka Jankowska et al. · European Journal of Medicinal Chemistry · 2018 · 36 citations · Full text

Medicinal Chemistry, Derivative (Chemistry), Health Sciences +15

Synthesis, 5-HT1A and 5-HT2A receptor affinity of new 1-phenylpiperazinylpropyl derivatives of purine-2,6- and pyrrolidine-2,5-diones

Maciej Pawłowski, Grażyna Chłoń‐Rzepa, Jolanta Obniska et al. · Il Farmaco · 2000 · 29 citations

Molecular Pharmacology, Medicinal Chemistry, Biochemistry +9