Valproic acid and chromatin remodeling in schizophrenia and bipolar disorder: Preliminary results from a clinical population

Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells

Martin Göttlicher · The EMBO Journal · 2001 · 1.9K citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +10

Histone Deacetylase Is a Direct Target of Valproic Acid, a Potent Anticonvulsant, Mood Stabilizer, and Teratogen

Christopher J. Phiel, Fang Zhang, Eric Yi‐Hsiu Huang et al. · Journal of Biological Chemistry · 2001 · 1.7K citations · Full text

Life Sciences, Molecular Biology, Pharmacology +17

Decrease in Reelin and Glutamic Acid Decarboxylase67 (GAD67) Expression in Schizophrenia and Bipolar Disorder

A Guidotti, James Auta, J M Davis et al. · Archives of General Psychiatry · 2000 · 1.2K citations

Life Sciences, Neurobiology, Neuroscience +17

Chromatin Remodeling Is a Key Mechanism Underlying Cocaine-Induced Plasticity in Striatum

Arvind Kumar, Kwang-Ho Choi, William Renthal et al. · Neuron · 2005 · 758 citations · Full text

Life Sciences, Neurobiology, Neuroscience +14

Mapping Global Histone Acetylation Patterns to Gene Expression

Siavash K. Kurdistani, Saeed Tavazoie, Michael Grunstein · Cell · 2004 · 639 citations · Full text

Life Sciences, Genetics, Molecular Biology +12