Multidomain Bcl-2 homolog Bax but not Bak mediates synergistic induction of apoptosis by TRAIL and 5-FU through the mitochondrial apoptosis pathway

Proapoptotic BAX and BAK: A Requisite Gateway to Mitochondrial Dysfunction and Death

Michael C. Wei, Wei‐Xing Zong, Emily H. Cheng et al. · Science · 2001 · 3.9K citations · Full text

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Bid, a Bcl2 Interacting Protein, Mediates Cytochrome c Release from Mitochondria in Response to Activation of Cell Surface Death Receptors

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Tumoricidal activity of tumor necrosis factor–related apoptosis–inducing ligand in vivo

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Life Sciences, Oncology, Pharmacology +12

Safety and antitumor activity of recombinant soluble Apo2 ligand

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tBID, a membrane-targeted death ligand, oligomerizes BAK to release cytochrome c

Michael C. Wei, Tullia Lindsten, Vamsi K. Mootha et al. · Genes & Development · 2000 · 1.3K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17