Concepedia

Optimal conditions for lentiviral transduction of engrafting human CD34+ cells

Naoya Uchida, Matthew M. Hsieh, Jun Hayakawa, C Madison, Kareem Washington, John F. Tisdale

Gene Therapy · 2011 · 59 citations · 45 references

DOI

Concepts

References

45

Gene Therapy of Human Severe Combined Immunodeficiency (SCID)-X1 Disease

Marina Cavazzana, Salima Hacein‐Bey, Geneviève de Saint Basile et al. · Science · 2000 · 2.6K citations

, , +17

NOD/SCID/γcnull mouse: an excellent recipient mouse model for engraftment of human cells

Mamoru Ito, Hidefumi Hiramatsu, Kimio Kobayashi et al. · Blood · 2002 · 1.5K citations

, , +11

Gene transfer by retrovirus vectors occurs only in cells that are actively replicating at the time of infection.

Mohammed Adam, A. Dusty Miller · Molecular and Cellular Biology · 1990 · 1.4K citations · Full text

, , +14

Transfusion independence and HMGA2 activation after gene therapy of human β-thalassaemia

Marina Cavazzana, Emmanuel Payen, Olivier Nègre et al. · Nature · 2010 · 1.3K citations

, , +12

Humanized mice in translational biomedical research

Leonard D. Shultz, Fumihiko Ishikawa, Dale L. Greiner · Nature reviews. Immunology · 2007 · 1.3K citations

, , +7